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These symptoms often occur at treatment initiation and may be mitigated by starting with lower doses and gradually increasing to the target dose
For innovator companies, this means that the window between patent expiry and first generic entry which has historically provided some runway for patient transition programs and revenue collection may compress
For Bicknell, data on the long-term effects will also be valuable
One storage trade-off: NaCl can speed aggregation in the vial over weeks. Mix smaller amounts and use within 12 weeks
46(9): Kern JK, Geier DA, Adams JB, Garver CR, Audhya T, Geier MR
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